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Friday, March 12, 2010

Bioinformatics Research Associate / Research Executive

Research Associate / Research Executive
The molecular modeling group supports Orchid’s drug discovery effort through the application of multiple computational approaches: structure-based design, virtual screening, library design, pharmacophore modeling, lead-hopping, QSAR and in silico ADME/Tox modeling.
As a molecular modeler, you are expected to support Orchid’s multi-disciplinary discovery teams in the hit identification and hit-to-lead optimization stage. You will contribute to our discovery efforts by applying multiple computational methodologies. A good understanding of computational principles and working knowledge about computational chemistry applications in drug discovery is required.
The position requires:
• A master’s degree in bioinformatics, biophysics or equivalent qualification.
• Minimum 2-3 years of work experience in pharmaceutical industry.
• Experience supporting discovery teams of medicinal chemistry, biology and PK/DM professionals.
• Experience applying various computational techniques in structure-based design and pharmacophore modeling.
• Experience with commercial computational chemistry software packages such as MOE, Schrodinger, Accelrys and Tripos.
• Experience in (i) programming/scripting or (ii) developing relational databases of small molecules is a plus.
Please email your CV mentioning the position applied for in the subject column to


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